A novel synthesis of thioamide derivatives of methyl vinyl ketone and their cyclization to 2 3 dihydro 4h thiopyran 4 ones were developed.
Methyl vinyl ketone reactions.
Butenone is the organic compound with the formula ch 3 c o ch ch 2 it is a reactive compound classified as an enone in fact the simplest example thereof it is a colorless flammable highly toxic liquid with a pungent odor.
Identification of the substance mixture and of the company undertaking.
The most widely used member of this class of compounds is methyl vinyl ketone ch 3 c o ch ch 2 which is useful in the robinson annulation reaction.
Signs and symptoms of methyl vinyl ketone exposure.
Fires involving methyl vinyl ketone may be extinguished with dry chemical co2 halon water spray alcohol or standard foam water spray or fog solid streams of water may be ineffective.
Tachycardia rapid heart beat hypothermia metabolic acidosis nausea and vomiting may be noted.
Since methyl vinyl ketone fires may produce toxic fumes when tank cars and trucks are involved isolate the area for 1 2 mile in all directions.
It is soluble in water and polar organic solvents.
Acute exposure of methyl vinyl ketone to the eyes may result in lacrimation ocular pain and irritation and corneal damage.
Enev4620 page 1 section 1.
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Lest there be confusion a ketone itself is a site of unsaturation.
Enev4620 vinyl methyl ketone 95 vinyl methyl ketone 95 safety data sheet enev4620 date of issue.